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Treatment
Sucrose and commercially available milk reduced crying in newborns during a blood collection procedure

https://doi.org/10.1136/ebn.1.1.10

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    Blass EM. Milk-induced hypoalgesia in human newborns. Pediatrics 1997 Jun; 99 : 825 –9. OpenUrlAbstract/FREE Full Text

    Objective

    To determine the effectiveness of milk and its components for reducing crying in newborns during and after a blood collection procedure.

    Design

    Randomised, double blind, controlled trial.

    Setting

    A community hospital in New York, USA.

    Patients

    72 vaginally delivered infants (42% boys, 85% white) with Apgar scores ≥ 8 at 1 minute and ≥ 9 at 5 minutes. 81% of the infants were breast fed.

    Intervention

    Infants were assigned to 1 of 9 treatment groups (8 infants per group): sucrose 12%; Ross Special Formula (a solution approximating human milk containing 7.5 ml protein, 3.24 g lactose, 1.85 ml fat, and water to make 50 ml); Similac, a commercially available milk; lactose 7%; fat/lactose (3.5 g lactose, 1.85 ml fat, and water to make 50 ml of solution); fat (1.85 ml of a coconut and soy oil blend and 48.15 …

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    Footnotes

    • Sources of funding: National Institutes of Mental Health and in part, Ross Products Division of Abbott Laboratories.

    • For article reprint: Dr E M Blass, Department of Psychology, Tobin Hall, University of Massachusetts, Amherst, MA 01003, USA. Fax +1 617 534 7297.