[HTML][HTML] Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

J Bordon, S Aliberti, R Fernandez-Botran… - International Journal of …, 2013 - Elsevier
Inflammation is a double-edged sword in the outcome of pneumonia. On the one hand, an
effective and timely inflammatory response is required to eliminate the invading respiratory …

The burden of community-acquired bacterial pneumonia in the era of antibiotic resistance

P Peyrani, L Mandell, A Torres… - Expert review of …, 2019 - Taylor & Francis
Introduction: Community-acquired pneumonia (CAP) is a significant global health problem
and leading cause of death and hospitalization in both the US and abroad. Increasing …

SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia

PGP Charles, R Wolfe, M Whitby, MJ Fine… - Clinical infectious …, 2008 - academic.oup.com
Background. Existing severity assessment tools, such as the pneumonia severity index (PSI)
and CURB-65 (tool based on confusion, urea level, respiratory rate, blood pressure, and …

Adults hospitalized with pneumonia in the United States: incidence, epidemiology, and mortality

JA Ramirez, TL Wiemken, P Peyrani… - Clinical Infectious …, 2017 - academic.oup.com
Background Understanding the burden of community-acquired pneumonia (CAP) is critical
to allocate resources for prevention, management, and research. The objectives of this study …

A worldwide perspective of atypical pathogens in community-acquired pneumonia

FW Arnold, JT Summersgill, AS LaJoie… - American journal of …, 2007 - atsjournals.org
Rationale: Controversy still exists in the international literature regarding the need to use
antimicrobials covering atypical pathogens when initially treating hospitalized patients with …

Future research directions in pneumonia. NHLBI working group report

CS Dela Cruz, RG Wunderink… - American journal of …, 2018 - atsjournals.org
Pneumonia is a complex pulmonary disease in need of new clinical approaches. Although
triggered by a pathogen, pneumonia often results from dysregulations of host defense that …

Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: an observational, multicentre cohort study

DH Kett, E Cano, AA Quartin, JE Mangino… - The Lancet infectious …, 2011 - thelancet.com
Summary Background The American Thoracic Society and Infectious Diseases Society of
America provide guidelines for management of hospital-acquired, ventilator-associated, and …

Acute myocardial infarction in hospitalized patients with community-acquired pneumonia

J Ramirez, S Aliberti, M Mirsaeidi… - Clinical infectious …, 2008 - academic.oup.com
Background. An epidemiological link between respiratory infection and acute myocardial
infarction (AMI) has been suggested, and recent data indicate that there is an association …

Thrombocytopenia and thrombocytosis at time of hospitalization predict mortality in patients with community-acquired pneumonia

M Mirsaeidi, P Peyrani, S Aliberti, G Filardo, J Bordon… - Chest, 2010 - Elsevier
Background Platelets are inflammatory cells with an important role in antimicrobial host
defenses. We speculate that an abnormal platelet count may be a marker of severity in …

Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization …

FW Arnold, AS LaJoie, GN Brock… - Archives of internal …, 2009 - jamanetwork.com
Background To define whether elderly patients hospitalized with community-acquired
pneumonia (CAP) had better outcomes if they were treated with empirical antimicrobial …