User profiles for "author:Jawad Sultan"

Sultan Abdul-Jawad

Research Associate, King's College London
Verified email at kcl.ac.uk
Cited by 2798

A new approach to prevention of knee osteoarthritis: reducing medial load in the contralateral knee

RK Jones, GJ Chapman, AH Findlow… - The Journal of …, 2013 - jrheum.org
Objective. Few if any prevention strategies are available for knee osteoarthritis (OA). In those
with symptomatic medial OA, the contralateral knee may be at high risk of disease, and a …

[HTML][HTML] A dynamic COVID-19 immune signature includes associations with poor prognosis

AG Laing, A Lorenc, I Del Molino Del Barrio, A Das… - Nature medicine, 2020 - nature.com
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …

[HTML][HTML] Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective …

L Monin, AG Laing, M Muñoz-Ruiz… - The Lancet …, 2021 - thelancet.com
Background The efficacy and safety profiles of vaccines against SARS-CoV-2 in patients
with cancer is unknown. We aimed to assess the safety and immunogenicity of the …

The range of the Oxford Shoulder Score in the asymptomatic population: a marker for post-operative improvement

F Younis, J Sultan, S Dix… - The Annals of The Royal …, 2011 - publishing.rcseng.ac.uk
INTRODUCTION The Oxford Shoulder Score (OSS) is a validated scoring system used to
assess the degree of pain and disability caused by shoulder pathology. To date there is no …

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

RK Gupta, S Abdul-Jawad, LE McCoy, HP Mok… - Nature, 2019 - nature.com
A cure for HIV-1 remains unattainable as only one case has been reported, a decade ago,.
The individual—who is known as the 'Berlin patient'—underwent two allogeneic …

[PDF][PDF] Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients

S Abdul-Jawad, L Baù, T Alaguthurai, IDM Del Barrio… - Cancer cell, 2021 - cell.com
Given the immune system's importance for cancer surveillance and treatment, we have
investigated how it may be affected by SARS-CoV-2 infection of cancer patients. Across …

The soluble isoform of CTLA‐4 as a regulator of T‐cell responses

FJ Ward, LN Dahal, SK Wijesekera… - European journal of …, 2013 - Wiley Online Library
CTLA‐4 is a crucial immune regulator that mediates both negative costimulation signals to T
cells, and regulatory T (Treg)‐cell extrinsic control of effector responses. Here we present …

[HTML][HTML] Novel conserved-region T-cell mosaic vaccine with high global HIV-1 coverage is recognized by protective responses in untreated infection

B Ondondo, H Murakoshi, G Clutton, S Abdul-Jawad… - Molecular Therapy, 2016 - cell.com
An effective human immunodeficiency virus type 1 (HIV-1) vaccine is the best solution for
halting the acquired immune deficiency syndrome epidemic. Here, we describe the design …

Interim results of the safety and immune-efficacy of 1 versus 2 doses of COVID-19 vaccine BNT162b2 for cancer patients in the context of the UK vaccine priority …

L Monin-Aldama, AG Laing, M Muñoz-Ruiz… - MedRxiv, 2021 - medrxiv.org
Background The efficacy and safety profile of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) have not been definitively established in …

A consensus Covid-19 immune signature combines immuno-protection with discrete sepsis-like traits associated with poor prognosis

AG Laing, A Lorenc, I Del Molino Del Barrio, A Das… - MedRxiv, 2020 - medrxiv.org
Person-to-person transmission of SARS-CoV-2 virus has triggered a global emergency
because of its potential to cause life-threatening Covid-19 disease. By comparison to …