Acetaminophen, aspirin, and caffeine (active drugs) v placebo for migraine headache
| Outcomes | Active drugs | Placebo | RBI (95% CI) | NNT (CI) |
|---|---|---|---|---|
| *Abbreviations defined in glossary; RBI, NNT, and CI calculated from data in article. | ||||
| Reduced pain at 2 h | 59% | 33% | 81% (59 to 106) | 4 (3 to 5) |
| Reduced pain at 6 h | 79% | 52% | 52% (40 to 66) | 4 (3 to 5) |
| No pain at 2 h | 21% | 7% | 192% (111 to 304) | 8 (6 to 10) |
| No pain at 6 h | 51% | 24% | 117% (84 to 155) | 4 (3 to 5) |
| No rescue drugs by 6 h | 88% | 73% | 20% (14 to 27) | 7 (5 to 10) |