Antibiotics v placebo for patients with sore throat in primary care settings (fixed effects model)*

OutcomesNo of studiesWeighted event ratesRRR (95% CI)NNT (CI)
AntibioticsPlacebo
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Rheumatic fever by 2 months11 1.4% 1.9%69% (53 to 80)186 (117 to 445)
Otitis media by 14 days10 1.5% 2.2%71% (47 to 84)144 (75 to 1923)
Quinsy by 2 months7 1.5% 2.4%81% (48 to 93)113 (58 to 2541)
Fever at day 3613.3%19.8%37% (19 to 51) 16 (10 to 35)
Throat soreness at day 31144%63%28% (23 to 33) 6 (5 to 7)
Headache at day 3224%44%45% (31 to 55) 5 (4 to 8)