Inhalation of β2 agonists from a metered dose inhaler with a holding chamber v inhalation from a nebuliser in acute asthma*

Weighted event rates
OutcomesPatientsNumber of RCTs (n)ChamberNebuliserRRR (95% CI)NNT
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Admission to hospitalAdults6 (352)13%15%12% (−38 to 46)Not significant
Children5 (353)12%16%35% (−6 to 60)Not significant