Age-adjusted relative risk (RR) of colon and rectal cancer for women who had ever used postmenopausal hormones compared with those who had never used hormones
| Type of cancer | Number of studies | RR (95% CI) | Heterogeneity |
|---|---|---|---|
| *Excluding studies that included premenopausal women in the “never used” group. †Significant heterogeneity existed among study results. | |||
| Colon | 18 | 0.80 (0.74 to 0.86) | p=0.02† |
| 13* | 0.76 (0.70 to 0.82) | p=0.32 | |
| Rectal | 10 | 0.81 (0.72 to 0.92) | p=0.03† |
| 7* | 0.81 (CI not available) | p=0.06† | |