4 diets with varying levels of macronutrients for weight loss in overweight and obese adults
| Mean weight loss at 2 years (kg) | |||
| Comparisons | Diet with higher macronutrient level | Diet with lower macronutrient level | Difference in weight loss, kg (95% CI)* |
| 25% v 15% protein | 3.6 | 3.0 | 0.6 (–0.4 to 1.6) |
| 40% v 20% fat | 3.3 | 3.3 | 0.0 (–1.0 to 0.9) |
| 65% v 35% carbohydrates | 2.9 | 3.4 | –0.6 (–1.9 to 0.8) |
*A positive difference indicates more weight loss with the diet with the higher macronutrient level.