Intensive v conventional treatment in type 2 diabetes and microalbuminuria†
| Outcomes (mean 7.8 y follow up) | Intensive | Conventional | Adjusted HR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Composite endpoint‡ | 24% | 44% | 0.47 (0.22 to 0.74) | 5 (3 to 19) |
| RRR (CI) | NNT (CI) | |||
|---|---|---|---|---|
| †HR = hazard ratio. Other abbreviations defined in glossary; RRR, NNT, and CI calculated from data provided by author. HR adjusted for baseline characteristics. ‡Composite endpoint of various cardiovascular events. | ||||
| Diabetic nephropathy | 20% | 39% | 48% (15 to 69) | 6 (4 to 22) |
| Retinopathy (developed or progressed) | 48% | 64% | 25% (1.5 to 44) | 7 (4 to 125) |
| Autonomic neuropathy | 30% | 54% | 44% (18 to 63) | 5 (3 to 12) |