Interventions | Number of RCTs | Number of patients | Overall effect: number of studies showing improvement or no difference |
---|---|---|---|
*RCTs = randomised controlled trials; GET = graded exercise therapy; CBT = cognitive behavioural therapy. Intervention duration ranged from 2 weeks to 1 year (mean 16 wks); follow up ranged from 2 weeks to 5 years. | |||
Behavioural | 8 | 883 | 6 improvement; 2 no difference |
GET | 3 | 350 | 3 improvement |
CBT | 5 | 533 | 3 improvement; 2 no difference |
Immunological | 9 | 440 | 4 improvement; 5 no difference |
Pharmacological | 12 | 896 | 2 improvement; 10 no difference |
Supplements | 5 | 174 | 2 improvement; 3 no difference |
Complementary or alternative | 2 | 84 | 1 improvement; 1 no difference |