Nutritional supplements v placebo or no supplements in patients being treated for active tuberculosis*
SupplementsOutcomesNumber of trials (n)Weighted event ratesRRR (95% CI)NNT (CI)
Vitamin DPositive sputum smear at 6 weeks2 (226)6% v 17%67% (24 to 86)9 (7 to 25)
Positive sputum smear at 8 weeks2 (267)6% v 6%0% (−149 to 60)NS
Multivitamin + trace elementDeath during follow-up3 (2190)24% v 24%2% (−13 to 15)NS
RRI (CI)NNH (CI)
Multivitamin + trace elementPositive sputum smear or culture at 1 month2 (1020)31% v 31%1% (−15 to 20)NS
  • *NS, not significant; other abbreviations defined in glossary. Weighted event rates, RRR, RRI, NNT, NNH, and CI calculated from data in article using a fixed-effect model.