Non-nutritive sucking v no provision of non-nutritive sucking for premature infants*

OutcomesNumber of studiesNumber of patientsWeighted mean difference95% CI
*All meta-analyses were based on a fixed effects model. Heterogeneity was significant only for the analysis of heart rate.
†Not significant.
Length of hospital stay 2 87−7.1 days−12.6 to −1.7
Weight gain 31031.57 g/day−0.37 to 3.5†
Heart rate 4126−1.4 beats/minute−5.9 to 3.1†
Oxygen saturation3 721.0%0.04 to 2.1†