Single dose paracetamol v placebo for ⩾50% pain relief within 4–6 hours after surgery*
| Dosage of paracetamol | Number of trials (n) | Event rates | RBI (95% CI) | NNT (CI) | |
|---|---|---|---|---|---|
| Paracetamol | Placebo | ||||
| *Abbreviations defined in glossary; RBI calculated from relative benefit data in article. | |||||
| †Information provided by author. | |||||
| 325 mg | 1 (100) | 69% | 43% | 60% (10 to 130) | 4 (3 to 14) |
| 500 mg | 6 (561) | 61% | 32% | 90% (60 to 130) | 4 (3 to 5) |
| 600/650 mg | 19 (1886) | 38% | 16% | 140% (100 to 180) | 5 (4 to 6) |
| 975/1000 mg | 23 {2759}† | 46% | 20% | 150% (120 to 180) | 4 (4 to 5) |
| 1500 mg | 1 (65) | 65% | 39% | 70% (20 to 140) | 4 (3 to 10) |