Aspirin v no aspirin and vitamin E v no vitamin E for patients with major cardiovascular risk factors*
| Outcomes at mean of 3.6 years | Comparison | Event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| *Combined endpoint = cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke. Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| Combined endpoint | Aspirin v no aspirin | 2.0% v 2.8% | 29% (−4 to 52) | Not significant |
| Cardiovascular death | Aspirin v no aspirin | 0.8% v 1.4% | 44% (1 to 69) | 166 (81 to 62500) |
| Total cardiovascular events | Aspirin v no aspirin | 6.3% v 8.2% | 23% (5 to 38) | 53 (30 to 258) |
| RRI (CI) | NNH | |||
| Combined endpoint | Vitamin E v no vitamin E | 2.5% v 2.3% | 7% (−56 to 26) | Not significant |