Aspirin v no aspirin and vitamin E v no vitamin E for patients with major cardiovascular risk factors*

Outcomes at mean of 3.6 yearsComparisonEvent ratesRRR (95% CI)NNT (CI)
*Combined endpoint = cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke. Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article.
Combined endpointAspirin v no aspirin2.0% v 2.8%29% (−4 to 52)Not significant
Cardiovascular deathAspirin v no aspirin0.8% v 1.4%44% (1 to 69)166 (81 to 62500)
Total cardiovascular eventsAspirin v no aspirin6.3% v 8.2%23% (5 to 38)53 (30 to 258)
Combined endpointVitamin E v no vitamin E2.5% v 2.3%7% (−56 to 26)Not significant