Event rates per patient-year | ||||
---|---|---|---|---|
Unfavourable outcomes | Oest + Prog | Placebo | RRI (95%CI) | NNH (CI) |
All cardiovascular disease | 1.57% | 1.32% | 22% (9 to 36) | 348 (213 to 848) |
Coronary heart disease | 0.37% | 0.30% | 29% (2 to 63) | 1152 (531 to 16 693) |
Stroke | 0.29% | 0.21% | 41% (7 to 85) | 1164 (562 to 6811) |
Venous thromboembolism | 0.34% | 0.16% | 111% (58 to 182) | 565 (345 to 1079) |
Invasive breast cancer | 0.38% | 0.30% | 26% (0 to 59) | 1285 (567 to infinity) |
Favourable outcomes | RRR (CI) | NNT (CI) | ||
---|---|---|---|---|
*Abbreviations defined in glossary; RRI, RRR, NNH, NNT, and CI calculated from hazard ratios, CIs, and control event rates in article. | ||||
Vertebral fracture | 0.09% | 0.15% | 34% (2 to 56) | 1962 (1191 to 33 358) |
Hip fracture | 0.10% | 0.15% | 34% (2 to 55) | 1962 (1213 to 33 358) |
Colorectal cancer | 0.10% | 0.16% | 37% (8 to 57) | 1691 (1097 to 7819) |