TY - JOUR T1 - Oestrogen plus progestin increased venous thromboembolic disease in postmenopausal women with coronary artery disease JF - Evidence Based Nursing JO - Evid Based Nurs SP - 123 LP - 123 DO - 10.1136/ebn.3.4.123 VL - 3 IS - 4 A2 - , Y1 - 2000/10/01 UR - http://ebn.bmj.com/content/3/4/123.abstract N2 - Grady D, Wenger NK, Herrington D, et al for the Heart and Estrogen/progestin Replacement Study Research Group.Postmenopausal hormone therapy increases risk for venous thromboembolic disease. The Heart and Estrogen/progestin Replacement Study.Ann Intern Med2000 May 2;132:689–96OpenUrlPubMedWeb of Science QUESTION: Does oestrogen plus progestin increase the risk of venous thromboembolic events in postmenopausal women with established coronary artery disease (CAD)? Randomised {allocation concealed}*, blinded (investigators, patients, outcome assessors), placebo controlled trial with mean follow up of 4.1 years (Heart and Estrogen/progestin Replacement Study [HERS]).20 clinical centres in the US.2763 postmenopausal women <80 years of age (mean age 67 y, 89% white) with established CAD but no previous venous thromboembolism and who had not had … ER -