Psychopathology among offspring of parents with substance abuse and/or anxiety disorders: a high-risk study

J Child Psychol Psychiatry. 1998 Jul;39(5):711-20.

Abstract

This paper reports the results of a high-risk study of children under age 18 of parents who served as probands in a family study of comorbidity of substance abuse and anxiety disorders. There was a strong degree of specificity of familial aggregation of both the anxiety disorders and substance disorders. Rates of conduct disorder and depression were elevated among offspring of all affected parents. Inclusion of co-parent disorders in the evaluation of familial transmission in the present study strengthened the findings regarding the specificity of transmission of the anxiety disorders and the links between both parental substance abuse and antisocial personality with child conduct disorder.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Alcoholism / genetics
  • Alcoholism / psychology
  • Antisocial Personality Disorder / genetics
  • Antisocial Personality Disorder / psychology
  • Anxiety Disorders / genetics
  • Anxiety Disorders / psychology*
  • Child
  • Child Behavior Disorders / genetics
  • Child Behavior Disorders / psychology*
  • Child of Impaired Parents / psychology*
  • Comorbidity
  • Female
  • Humans
  • Male
  • Personality Assessment / statistics & numerical data
  • Psychometrics
  • Substance-Related Disorders / genetics
  • Substance-Related Disorders / psychology*