Midazolam syrup as a premedication to reduce the discomfort associated with pediatric intravenous catheter insertion

Mara McErlean; Joel M Bartfield; Tanuja A Karunakar; Mark C W Whitman; Dawn M Turley

doi:10.1067/mpd.2003.62

Midazolam syrup as a premedication to reduce the discomfort associated with pediatric intravenous catheter insertion

J Pediatr. 2003 Apr;142(4):429-30. doi: 10.1067/mpd.2003.62.

Authors

Mara McErlean¹, Joel M Bartfield, Tanuja A Karunakar, Mark C W Whitman, Dawn M Turley

Affiliation

¹ Department of Emergency Medicine, Albany Medical College, Albany, New York 12208, USA.

PMID: 12712062
DOI: 10.1067/mpd.2003.62

Abstract

This randomized, double-blind, placebo-controlled study evaluated midazolam syrup for reducing discomfort from intravenous placement in children 9 months to 6 years. Parents and observers rated the child's discomfort by using visual analogue scales. Median parents' pain scores were significantly lower in the midazolam than the placebo group (P =.002). Midazolam effectively reduces discomfort associated with intravenous insertion.

Publication types

Clinical Trial
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Administration, Oral
Catheterization, Central Venous / adverse effects*
Child
Child, Preschool
Double-Blind Method
Female
Humans
Hypnotics and Sedatives / administration & dosage*
Hypnotics and Sedatives / therapeutic use*
Infant
Male
Midazolam / administration & dosage*
Midazolam / therapeutic use*
Pain / etiology*
Pain / prevention & control*
Pain Measurement
Premedication*
Prospective Studies

Substances

Hypnotics and Sedatives
Midazolam