A comparison of the effects of oral conjugated equine estrogen and transdermal estradiol-17β combined with an oral progestin on quality of life in postmenopausal women
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Quality of life of patients with bilateral oophorectomy before the age of 45 for the treatment of endometriosis
2022, MaturitasCitation Excerpt :This could be considered as surprising since more than 71% of the women indicated still experiencing hot flushes although there was no significant difference in the mean vasomotor domain score between current HRT users and non-users. This is in contrast to the results of most studies, which reported an improvement in every domain of the MenQOL questionnaire in postmenopausal women who were treated with menopause hormone therapy [41–45]. It is more likely that there is a lack of power in our study since there was a clear trend towards worser scores in the vasomotor domain in untreated women compared to current users.
The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation
2011, Gynecologic OncologyCitation Excerpt :The majority of women who were premenopausal at the time of surgery had a significant worsening of vasomotor symptoms after surgery (hot flashes, night sweats and sweating) (p < 0.0001) and a decline in sexual functioning (decrease in sexual desire, vaginal dryness, and avoidance of intimacy) (p < 0.0001). Compared to published norms [20,26], women who were premenopausal at the time of surgery decreased in these domains to levels similar to women who are two to seven years post-menopause (see Table 3). Women who were taking HRT had significantly fewer vasomotor symptoms (p = 0.0003) and reported better sexual functioning (p = 0.015) after surgery than women who were not taking HRT.
Issues Relating to Quality of Life in Postmenopausal Women and Their Measurement
2007, Treatment of the Postmenopausal Woman: Basic and Clinical Aspects, Third Edition