Elsevier

American Heart Journal

Volume 128, Issue 5, November 1994, Pages 879-884
American Heart Journal

Physical activity and mortality in women in the Framingham Heart Study

https://doi.org/10.1016/0002-8703(94)90583-5Get rights and content

Abstract

Men who are more active live longer, but it is not clear if the same is true for women. We monitored 1404 women aged 50 to 74 who were free of cardiovascular disease. We assessed physical activity levels and ranked subjects into quartiles. After 16 years, 319 (23%) women had died. The relative risk of mortality, compared to the least active quartile, was as follows: second quartile, 0.95 (95% confidence interval [Cl] 0.72 to 1.26); third quartile, 0.63 (95% Cl 0.46 to 0.86); most active quartile, 0.67 (95% Cl 0.48 to 0.92). The relative risks were not changed by adjustment for cardiac risk factors, chronic obstructive pulmonary disease, or cancer or by excluding all subjects who died in the first 6 years (to eliminate occult disease at baseline). There was no association between activity levels and cardiovascular morbidity or mortality. We conclude that women who were more active lived longer; this effect was not the result of decreased cardiovascular disease.

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    Supported by the Framingham Heart Study Visiting Scholar's Fund, which includes support from the National Heart, Lung, and Blood Institute; ICI Pharma; Merck, Sharp, and Dohme; and Pfizer Inc.

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