Table of contents

Therapeutics

• Systematic review: Intensive glucose control in type 2 diabetes reduces cardiovascular disease, but not cardiovascular or all-cause mortality, and increases risk of severe hypoglycaemia (23 February, 2010)

  Deborah Chyun
• Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects (23 February, 2010)

  Cliff Richardson
• Systematic review: Combined educational and contraceptive interventions reduce unplanned teenage pregnancy, but effects on other outcomes such as sexually transmitted infections unclear (23 February, 2010)

  Elizabeth Grigg
• Randomised controlled trial: 3-month physiotherapy and occupational therapy programme did not improve mobility and independence in older care home residents with limitations in these areas (23 February, 2010)

  Hye-A Yeom
• Randomised controlled trial: “Hospital at home” care shows similar mortality and subsequent hospital admissions to hospital care for older patients with acutely decompensated chronic heart failure (23 February, 2010)

  Sue Ashby
• LEAP 2 randomised controlled trial: Primary care screening and brief counselling for overweight or mildly obese children does not improve BMI, nutrition or physical activity (23 February, 2010)

  Fiona Milligan
• ENABLE II randomised controlled trial: Nurse-led multicomponent psychoeducational palliative intervention improves quality of life and mood in patients with advanced cancer (23 February, 2010)

  Carole Willard
• Randomised controlled trial: Ibuprofen provides similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures (23 February, 2010)

  Carie A Braun
• Randomised controlled trial: Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction (23 February, 2010)

  Matthias Briel
• Systematic review: Prebiotic supplementation of formula milk increases stool counts of bifidobacteria and lactobacilli compared with unsupplemented formula milk in full-term neonates (23 February, 2010)

  Yvan Vandenplas
• Systematic review: Simple physical interventions such as handwashing and wearing masks can reduce spread of epidemic respiratory viruses (23 February, 2010)

  Mary Lou Manning
• Randomised controlled trial: Partner-assisted emotional disclosure intervention may improve relationship quality in couples where one partner has gastrointestinal cancer and has difficulty discussing cancer-related concerns (23 February, 2010)

  D Kelly
• Randomised controlled trial: A multifaceted distraction intervention may reduce pain and discomfort in children 4–6 years of age receiving immunisation (23 February, 2010)

  Lindsey L Cohen
• Randomised controlled trial: 0.2% topical lidocaine reduces pain during and immediately after vacuum-assisted closure dressing changes, but effects may be short lived (23 February, 2010)

  Kevin Y Woo
• Systematic review: Preventive antibiotics reduce infections but not mortality in adults with acute stroke (23 February, 2010)

  Peter Langhorne
• Systematic review: Effects of physical fitness training on mortality, independence and disability after stroke unclear (23 February, 2010)

  Barbara J Lutz
• Systematic review: Low-quality evidence that atovaquone-proguanil and doxycycline are better tolerated prophylactic antimalarial regimens in travellers than mefloquine (23 February, 2010)

  Michael Hawkes
• Systematic review: Little evidence from randomised controlled trials regarding effects of routine health promotion interventions for pregnant women (23 February, 2010)

  Mary M Aruda
• Randomised controlled trial: Supportive counselling may improve academic performance more than ordinary counselling in underachieving male nursing students (23 February, 2010)

  Nasim Kanji
• Randomised controlled trial: Neonatal Parent Baby Interaction Programme does not affect mental or psychomotor development of preterm infants at corrected age 2 years (23 February, 2010)

  Mary Margaret Gottesman
• Systematic review: Neuraminidase inhibitors produce a small reduction in duration of seasonal flu in children and reduce transmission in affected households, but effects on serious complications are unclear (23 February, 2010)

  Karen J Ford, Claire Waddington
• Randomised controlled trial: Internet-based asthma self-management program for adults improves asthma control and lung function, but does not reduce exacerbations (23 February, 2010)

  Mark L Levy
• Randomised controlled trial: Diabetes Medication Choice cards improve patient knowledge and involvement in decision-making, but do not improve medication adherence or glycaemic control (23 February, 2010)

  Karen Chang