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Implications for practice and research
Paracetamol may be the first choice of treatment for soft tissue injuries because of less adverse events and similar efficacy as non-steroidal anti-inflammatory drugs (NSAIDs).
Additional randomised controlled trials (RCTs) are required to determine if there is a difference in return to function or adverse effects between non-selective and COX-2 selective NSAIDs versus paracetamol.
Future research should also focus on very old and very young people.
Acute soft tissue injuries are common especially in sport activities. These injuries are responsible for a high number of emergency department attendances and high socioeconomic costs. Acute soft tissue injuries include a number of conditions such as sprain, strain, …
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