Elastic compression stockings fail to prevent post-thrombotic syndrome after a first deep vein thrombosis
- Department of Pharmacy Practice, MCPHS University, Worcester, Massachusetts, USA
- Correspondence to: Dr Abir Kanaan, Department of Pharmacy Practice, MCPHS University, 19 Foster Street, Worcester, MA 01608, USA;
Implications for practice and research
Elastic compression stockings should not be routinely used for the prevention of post-thrombotic syndrome (PTS) following a first deep vein thrombosis (DVT) episode.
The role of elastic compression stockings in PTS prevention should be further examined.
Post-thrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT) characterised by clinical features ranging from minor limb swelling to leg ulceration. One in three patients with DVT will develop PTS sequelae within 5 years, with most cases reported within the first 2 years.1 Venous hypertension, resulting from valvular reflux and residual thrombus, is implicated in the pathophysiology of PTS.2 Elastic compression stockings reduce venous hypertension and have been evaluated …