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Cohort study
Hypertension during pregnancy is associated with increased risk of chronic and end-stage kidney disease
  1. Reem A Asad,
  2. Vesna D Garovic
  1. Department of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
  1. Correspondence to: Dr Vesna D Garovic
    Department of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA, garovic.vesna{at}mayo.edu

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Implications for practice and research

  • Women with a history of hypertensive pregnancy disorders may have an elevated risk of future chronic kidney disease (CKD) and end-stage renal disease (ESRD).

  • Follow-up of renal function and proteinuria after pre-eclamptic pregnancies could facilitate early detection and intervention of renal disease.

Context

To date, case–control and registry-based cohort studies have suggested that women with histories of hypertensive pregnancy disorders and pre-eclampsia in particular, are at risk for future cardiovascular disease (CVD).1 ,2 Limited data have suggested that women with pre-eclampsia are at risk for microalbuminuria,3 CKD and ESRD years after their affected pregnancies.4 The limitations of the available evidence …

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