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Commentary on: Climo MW, Yokoe DS, Warren DK, et al. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med 2013;368:533–42.
Implications for practice and research
Chlorhexidine-impregnated wash cloths have been shown to have some effect on multidrug-resistant acquisition and hospital-acquired blood stream infections in intensive care settings.
Further research, including cost-effectiveness, is required to confirm these findings in intensive care units and in other healthcare settings.
Hospital-acquired blood stream infections (BSI) remain as an important cause of morbidity and mortality in intensive care units (ICUs) and other high-risk settings. Incidence rates vary considerably, depending on factors such as patient characteristics, type of invasive procedures, infection control practices, definitions and duration of hospital stay. Recently reported BSI rates in intensive care settings range between 0.28 and 22 per 1000 ICU patient-days1 ,2 and mortality may be as high …
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