No evidence that introduction of allergenic foods prior to 6 months of age increases reports of wheeze or eczema in young childhood
- Department of Clinical and Experimental Sciences, Southampton General Hospital, Southampton, UK
- Correspondence to S Hasan Arshad
Department of Clinical and Experimental Sciences, Southampton General Hospital, Tremona Road, Southampton, Hants SO16 6YD, UK;
Implications for practice and research
■ A delay in the introduction of solid foods beyond 6 months does not protect from allergic disease and should not be recommended.
■ A randomised controlled trial (RCT) investigating the specific effect of early versus delayed introduction of solid foods is needed.
A delay in introduction of solid foods has been suggested for decades as a means of preventing atopic diseases due to infants' immature immune system and hence inability to handle a wide variety of food antigens.1 The normal response to food antigens is that of immune tolerance. However, …