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Randomised controlled trial
Administration of annual oral high-dose vitamin D to community dwelling older women in autumn and winter months increases risk of falls and fractures
  1. Cathy R Kessenich
  1. University of Tampa, Tampa, Florida, USA
  1. Correspondence to Cathy R Kessenich
    401 W. Kennedy Blvd, Tampa, FL 33606, USA; ckessenich{at}ut.edu

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Vitamin D deficiency is an increasingly important worldwide issue. It is estimated that one billion people worldwide have vitamin D deficiency or insufficiency.1 Vitamin D deficiency has been linked to a multitude of problems across the lifespan. The importance of vitamin D and calcium absorption has been well documented. What remains unclear is the role of vitamin D in osteoporotic fracture prevention and specifically, the amount and regimen of vitamin D ingestion that is safe and effective in decreasing falls and subsequent fractures.

Study details

Sanders and colleagues conducted the largest randomised clinical trial to date of the effects of giving a year's supply of vitamin D in a single dose. The study hypothesis …

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