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Vitamin D deficiency is an increasingly important worldwide issue. It is estimated that one billion people worldwide have vitamin D deficiency or insufficiency.1 Vitamin D deficiency has been linked to a multitude of problems across the lifespan. The importance of vitamin D and calcium absorption has been well documented. What remains unclear is the role of vitamin D in osteoporotic fracture prevention and specifically, the amount and regimen of vitamin D ingestion that is safe and effective in decreasing falls and subsequent fractures.
Sanders and colleagues conducted the largest randomised clinical trial to date of the effects of giving a year's supply of vitamin D in a single dose. The study hypothesis …
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