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Management of critically ill patients with a pulmonary artery catheter did not reduce all cause mortality

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 Q In critically ill patients, does management with a pulmonary artery catheter (PAC) reduce hospital all cause mortality?

METHODS

Embedded ImageDesign:

randomised controlled trial (Pulmonary Artery Catheters in Management of patients in intensive care [PAC-Man] trial).

Embedded ImageAllocation:

concealed.

Embedded ImageBlinding:

unblinded.

Embedded ImageFollow up period:

until discharge from the acute hospital ward.

Embedded ImageSetting:

65 intensive care units (ICUs) in the UK.

Embedded ImagePatients:

1041 patients (mean age 65 y, 57% men) who were admitted to adult ICUs and identified by the treating clinicians as patients who should be managed with a PAC. Exclusion criteria included age <16 years, elective admission for preoperative optimisation, presence of a PAC on admission, or haemodynamic optimisation before organ donation.

Embedded ImageIntervention:

management with a PAC (n = 519) or without a PAC (n = 522). The timing …

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