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Evid Based Nurs 9:49 doi:10.1136/ebn.9.2.49
  • Treatment

Inhaled insulin added to or replacing 2 oral agents reduced haemoglobin A1c concentrations in type 2 diabetes

Inhaled insulin plus 2 oral agents (II2A) and inhaled insulin monotherapy (II) v 2 oral agents (2A) for type 2 diabetes*

Outcomes at 12 weeks Comparison Event rates RBI (95% CI) NNT (CI)
*Abbreviations defined in glossary; event rates, RBI, RRI, NNT, NNH, and CI calculated from data in article.
Haemoglobin A1c concentration <8% II2A v 2A 86% v 19% 359% (207 to 609) 2 (2 to 2)
II v 2A 56% v 19% 198% (93 to 372) 3 (3 to 5)
Haemoglobin A1c concentration <7% II2A v 2A 32% v 1% 2972% (454 to 17536) 4 (3 to 5)
II v 2A 17% v 1% 1500% (182 to 9260) 7 (5 to 12)
RRI (CI) NNH (CI)
Hypoglycaemia II2A v 2A 78% v 8.3% 836% (396 to 1734) 2 (2 to 2)
II v 2A 68% v 8.3% 712% (327 to 1498) 2 (2 to 3)

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