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A simple risk score predicted 7 day stroke risk after transient ischaemic attack

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 Q Can a simple risk score predict stroke during the first 7 days after probable or definite transient ischaemic attack (TIA)?

METHODS

Embedded ImageDesign:

3 cohort studies: a derivation cohort (Oxfordshire Community Stroke Project [OCSP]) and 2 independent validation cohorts (2 cohorts from the Oxford Vascular Study [OXVASC] and a cohort of patients referred to a hospital based TIA clinic).

Embedded ImageSetting:

10 family practices in Oxfordshire, UK (OCSP and OXVASC cohorts) and a hospital based TIA clinic.

Embedded ImagePatients:

209 patients (mean age 70 y) with a first ever probable or definite TIA (OCSP derivation cohort); 190 patients (mean age 74 y) with probable or definite TIA and 378 patients (mean age 70 y) with suspected TIA (OXVASC validation cohorts); and 210 patients (mean age 65 y) referred to the hospital clinic with suspected TIA (clinic validation cohort).

Embedded ImageDescription of prediction guide:

analysis of predefined risk factors in the derivation cohort found that age ⩾60 years, clinical features, …

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