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Q In elderly people, do multivitamins and mineral supplements reduce the risk of infections more than placebo?
AMED, Biological Abstracts, British Nursing Index, CINAHL, Science and Social Science Citation Indexes, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, EBM reviews, EMBASE/Excerpta Medica, IBIDS, Medline, NHS Centre for Reviews and Dissemination databases, and PreMedline (1966 to January 2004); searches of published reviews, guidelines, Health Evidence Bulletin Wales, and conference abstracts; and reference lists of relevant articles.
Study selection and assessment:
randomised controlled trials (RCTs) that compared the effects of a combination of multivitamins and mineral supplements with placebo in elderly people and reported infection related outcomes. Study quality was assessed using the 5 point Jadad scale.
days with infection, incidence of ⩾1 infection during the study period, infection rate, and adverse events.
Of the 8 RCTs that met the selection criteria, 5 had Jadad scale scores of 4 out of …
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