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Review: multivitamins and mineral supplements do not reduce infections in elderly people

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 Q In elderly people, do multivitamins and mineral supplements reduce the risk of infections more than placebo?

METHODS

Embedded ImageData sources:

AMED, Biological Abstracts, British Nursing Index, CINAHL, Science and Social Science Citation Indexes, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, EBM reviews, EMBASE/Excerpta Medica, IBIDS, Medline, NHS Centre for Reviews and Dissemination databases, and PreMedline (1966 to January 2004); searches of published reviews, guidelines, Health Evidence Bulletin Wales, and conference abstracts; and reference lists of relevant articles.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) that compared the effects of a combination of multivitamins and mineral supplements with placebo in elderly people and reported infection related outcomes. Study quality was assessed using the 5 point Jadad scale.

Embedded ImageOutcomes:

days with infection, incidence of ⩾1 infection during the study period, infection rate, and adverse events.

MAIN RESULTS

Of the 8 RCTs that met the selection criteria, 5 had Jadad scale scores of 4 out of …

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