Evid Based Nurs 9:22 doi:10.1136/ebn.9.1.22
  • Treatment

An educational booklet did not improve adherence or symptoms in patients prescribed thyroxine for primary hypothyroidism

 Q Does an educational booklet addressing lay health beliefs about medicine-taking improve adherence in patients prescribed thyroxine for primary hypothyroidism?



randomised controlled trial.


{not concealed}.*


blinded (laboratory staff assessing thyroid stimulating hormone [TSH] assays).

GraphicFollow up period:

median 96 days.


3 suburban general practices (18 physicians) in northwest England, UK.


332 patients ⩾18 years of age (mean age 62 y, 92% women) who were taking a stable dose of thyroxine (ie, dose unchanged over the previous 8 wks) for primary hypothyroidism caused by thyroidectomy, radio-iodine treatment, or autoimmune thyroiditis. Patients with serious illness were excluded.


166 patients were allocated to receive an educational booklet by post a few days after the initial assessment; …

No Related Web Pages

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article