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Treatment
Glargine dose titration by patients and by physicians were equally effective for preventing severe hypoglycaemia

https://doi.org/10.1136/ebn.9.1.20

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    Davies M, Storms F, Shutler S, et al. Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care 2005;28:1282–8.OpenUrlAbstract/FREE Full Text

    Q In patients with suboptimally controlled type 2 diabetes mellitus, is insulin glargine dose titration by a physician equivalent to titration by the patient for preventing severe hypoglycaemia and improving glycaemic control?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    unclear concealment.

    Embedded ImageBlinding:

    unblinded

    Embedded ImageFollow up period:

    24 weeks.

    Embedded ImageSetting:

    611 centres in 59 countries in western and eastern Europe, South America, Asia, and Africa/Middle East.

    Embedded ImagePatients:

    5033 patients ⩾18 years of age (mean age 58 y, 52% women) who had suboptimally controlled type 2 diabetes mellitus (ie, …

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    Footnotes

    • For correspondence: Dr M Davies, University Hospitals of Leicester, Leicester, UK. melanie.davies{at}uhl-tr.nhs.uk

    • Source of funding: Sanofi-Aventis.