Glargine dose titration by patients and by physicians were equally effective for preventing severe hypoglycaemia
Q In patients with suboptimally controlled type 2 diabetes mellitus, is insulin glargine dose titration by a physician equivalent to titration by the patient for preventing severe hypoglycaemia and improving glycaemic control?
METHODS
Design:
randomised controlled trial.
Allocation:
unclear concealment.
Blinding:
unblinded
Follow up period:
24 weeks.
Setting:
611 centres in 59 countries in western and eastern Europe, South America, Asia, and Africa/Middle East.
Patients:
5033 patients ⩾18 years of age (mean age 58 y, 52% women) who had suboptimally controlled type 2 diabetes mellitus (ie, required basal long acting insulin for control of hyperglycaemia), glycated haemoglobin [HbA1C] concentrations >7.0 and <12.0%, and body mass index <40 kg/m2. Exclusion criteria …
