Evid Based Nurs 9:20 doi:10.1136/ebn.9.1.20
  • Treatment

Glargine dose titration by patients and by physicians were equally effective for preventing severe hypoglycaemia

 Q In patients with suboptimally controlled type 2 diabetes mellitus, is insulin glargine dose titration by a physician equivalent to titration by the patient for preventing severe hypoglycaemia and improving glycaemic control?



randomised controlled trial.


unclear concealment.



GraphicFollow up period:

24 weeks.


611 centres in 59 countries in western and eastern Europe, South America, Asia, and Africa/Middle East.


5033 patients ⩾18 years of age (mean age 58 y, 52% women) who had suboptimally controlled type 2 diabetes mellitus (ie, required basal long acting insulin for control of hyperglycaemia), glycated haemoglobin [HbA1C] concentrations >7.0 and <12.0%, and body mass index <40 kg/m2. Exclusion criteria …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article