Aspirin, 1000 mg, v placebo for acute migraine with moderate to severe pain*
| Outcomes at 2 hours | Aspirin | Placebo | RBI (95% CI) | NNT (CI) |
|---|---|---|---|---|
| *Abbreviations defined in glossary; RBI, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| †Response = change in pain intensity from moderate or severe at baseline to mild or none. | ||||
| Response† | 52% | 34% | 53% (21 to 94) | 6 (4 to 12) |
| Pain free | 20% | 6% | 233% (83 to 513) | 8 (5 to 14) |
| Resolution of nausea | 52% | 43% | 21% (−2 to 49) | Not significant |
| Resolution of photophobia | 30% | 14% | 114% (44 to 221) | 7 (5 to 13) |
| Resolution of phonophobia | 34% | 17% | 100% (40 to 188) | 6 (4 to 12) |
| RRI (95% CI) | NNH | |||
| Any adverse event over 24 hours | 8.8% | 4.9% | 79% (−14 to 273) | Not significant |
