|Outcomes at 2 hours||Aspirin||Placebo||RBI (95% CI)||NNT (CI)|
|*Abbreviations defined in glossary; RBI, RRI, NNT, NNH, and CI calculated from data in article.|
|†Response = change in pain intensity from moderate or severe at baseline to mild or none.|
|Response†||52%||34%||53% (21 to 94)||6 (4 to 12)|
|Pain free||20%||6%||233% (83 to 513)||8 (5 to 14)|
|Resolution of nausea||52%||43%||21% (−2 to 49)||Not significant|
|Resolution of photophobia||30%||14%||114% (44 to 221)||7 (5 to 13)|
|Resolution of phonophobia||34%||17%||100% (40 to 188)||6 (4 to 12)|
|RRI (95% CI)||NNH|
|Any adverse event over 24 hours||8.8%||4.9%||79% (−14 to 273)||Not significant|
Aspirin, 1000 mg, reduced moderate to severe pain in acute migraine headache
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