rss
Evid Based Nurs 8:86 doi:10.1136/ebn.8.3.86
  • Treatment

Review: statins reduce non-fatal and fatal strokes in patients with and without coronary heart disease

Statins v control interventions for prevention of non-fatal and fatal stroke (follow up 0.5 to 6.1 y)*

Weighted event rates
Patients Number of trials (n) Statins Control RRR (95% CI) NNT (CI)
*CHD  =  coronary heart disease; other abbreviations defined in glossary. RRR, NNT, and CI calculated from data in article using a random effects model. Patients in 6 of the 29 statin trials could not be classified as having or not having CHD because 10–90% of patients had CHD.
With and without CHD 29 (93 399) 3.2% 3.6% 18% (10 to 24) 220 (140 to 504)
With CHD 17 (25 718) 2.6% 3.2% 25% (13 to 35) 190 (112 to 634)
Without CHD 6 (19 567) 1.4% 1.9% 23% (5 to 38) 159 (129 to 1667)

This Article

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article