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Treatment
Review: statins reduce non-fatal and fatal strokes in patients with and without coronary heart disease

https://doi.org/10.1136/ebn.8.3.86

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    Briel M, Studer M, Glass TR, et al. Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med 2004;117:596–606.OpenUrlCrossRefPubMedWeb of Science

    Q In patients with and without coronary heart disease (CHD), what are the effects of lipid lowering interventions (statins, fibrates, resins, n-3 fatty acids, and diet) for preventing non-fatal and fatal strokes?

    METHODS

    Embedded ImageData sources:

    Medline, EMBASE/Excerpta Medica, Pascal, and Index Medicus (all from inception to August 2002); Cochrane Library (searched August 2002); bibliographies of relevant articles; and contact with investigators.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) in any language that compared dietary or pharmaceutical lipid lowering interventions with placebo or usual diet, had follow up ⩾6 months, and had …

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    Footnotes

    • For correspondence: Dr M Briel, Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland. brielmuhbs.ch

    • Source of funding: no external funding.