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Evid Based Nurs 8:84 doi:10.1136/ebn.8.3.84
  • Treatment

Review: mild induced hypothermia does not reduce mortality or severe disability in moderate to severe head injury

Hypothermia v normothermia for moderate to severe head injury*

Weighted event rates
Outcomes at 3–12 months Number of trials (n) Hypothermia Normothermia RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article using a fixed effects model.
All cause mortality 12 (1061) 28% 33% 14% (−3 to 28) Not significant
Death or severe disability 9 (746) 50% 57% 12% (0 to 23) Not significant
RRI (CI) NNH (CI)
Pneumonia 7 (281) 44% 29% 51% (10 to 108) 7 (4 to 25)

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