|Number of trials (n)||Vitamin E dose||RRI (95% CI)||Risk difference per 10 000 persons (CI)||NNH (CI)|
|*Abbreviations defined in glossary; RRI, RRR, NNH NNT, and CI calculated from data in article. Follow up ranged from 1.4 to 8.2 years. A dose-response regression model was used.|
|†Favours placebo or no vitamin E.|
|19 (135 967)||High and low||1% (−2 to 4)||10 (−18 to 38)||Not significant|
|11 (40 950)||High||4% (1 to 7)||39 (3 to 74)†||257 (136 to 3334)|
|8 (95 017)||Low||2% (−1 to 4)||−16 (−41 to 10)||Not significant|
Review: high dose vitamin E supplementation is associated with increased all cause mortality
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