Evid Based Nurs 8:81 doi:10.1136/ebn.8.3.81
  • Treatment

A collaborative care intervention improved depression outcomes, but not glycaemic control, in diabetes and comorbid depression

 Q In patients with diabetes mellitus and comorbid major depression or dysthymia, does a pathways collaborative care intervention (PCCI) for depression improve both depression and glycaemic control outcomes?



randomised controlled trial.




blinded (outcome assessors).

GraphicFollow up period:

12 months


9 Group Health Cooperative primary care clinics in western Washington, USA.


329 ambulatory patients (mean age 58 y, 65% women) with diabetes mellitus and comorbid major depression or dysthymia. Exclusion criteria included care from a psychiatrist, confusion suggestive of dementia, or a diagnosis of bipolar disorder or schizophrenia.


a PCCI (n = 164) or usual care (UC) (n = 165). The PCCI was an individualised, stepped care depression treatment programme delivered by a depression clinical specialist nurse in collaboration with …

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