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Q In patients with asthma, is budesonide (BUD) plus formoterol (FORM) (BUDFORM) for both maintenance and symptom relief more effective than fixed dosing using BUDFORM or a 4 fold higher dose of BUD, both with a short acting β2 agonist (SABA), for reducing the rate of severe asthma exacerbations?
randomised controlled trial.
blinded (patients and healthcare providers).
Follow up period:
246 centres in 22 countries.
2760 outpatients (mean age 36 y, 55% women/girls; 12% children 4–11 y) with asthma who were using inhaled corticosteroids (ICSs).
BUDFORM (BUD, 80 μg plus FORM, 4.5 μg) both for …
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