Evid Based Nurs 8:58 doi:10.1136/ebn.8.2.58
  • Assessment (screening or diagnosis)

Review: a low clinical probability plus a normal d-dimer test result excludes a diagnosis of deep venous thrombosis

A combination of rapid d-dimer testing and estimation of clinical probability for excluding a diagnosis of deep venous thrombosis*

D-dimer test result Estimated clinical probability 3 month cumulative incidence of venous thrombosis (95% CI)
*CI defined in glossary.
Normal on the SimpliRED d-dimer test Low 0.5% (0.07 to 1.1)
Moderate 3.5% (1.4 to 6.9)
High 21% (8.5 to 38)
Normal on the highly sensitive d-dimer tests Low or moderate 0.4% (0.04 to 1.1)
High 6.4% (1.7 to 15)

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