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Evid Based Nurs 8:55 doi:10.1136/ebn.8.2.55
  • Treatment

Review: magnesium prophylaxis after cardiac surgery reduces the risk of arrhythmia and atrial fibrillation

Shiga T, Wajima Z, Inoue T, et al. Magnesium prophylaxis for arrhythmias after cardiac surgery: a meta-analysis of randomized controlled trials. Am J Med 2004;117:325–33.


 
 Q Does magnesium prophylaxis after cardiac surgery reduce the risk of arrhythmia?

METHODS

GraphicData sources:

Medline (1966 to June 2003), EMBASE/Excerpta Medica (1980 to June 2003), Cochrane Controlled Trials Register (Issue 3, 2003), and hand searches of references of reports and reviews.

GraphicStudy selection and assessment:

randomised controlled trials (RCTs) in any language that compared a single, fixed dose of prophylactic magnesium (intravenous, central, or intracoronary administration) with control (placebo or routine care) after cardiac surgery. 2 independent reviewers assessed the methodological quality of individual trials using the 5 point Jadad scale.

GraphicOutcomes:

atrial fibrillation (AF), supraventricular arrhythmia (SA) and ventricular arrhythmia (VA), serum magnesium concentration on postoperative day 1, length of hospital stay, myocardial infarction (MI), and mortality.

MAIN RESULTS

17 RCTs (n = 2069) met the selection criteria. 9 studies had …

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