Review: a single dose of oral naproxen or naproxen sodium reduced acute postoperative pain in adults
Q Is a single dose of oral naproxen or naproxen sodium effective and safe for acute postoperative pain in adults?
Cochrane Library (Issue 4, 2002), Medline and PreMedline (1966–2002), PubMed (1966–2002), EMBASE/Excerpta Medica (1980–2002), Oxford Pain Relief Database (based on 40 hand searched journals from 1954–94), unpublished trials held in house, and reference lists of retrieved articles.
Study selection and assessment:
published and unpublished randomised, double blind, clinical trials in any language that compared a single oral dose of naproxen or naproxen sodium with placebo (⩾10 patients/group) in adults (⩾12 y) with moderate to severe pain after a surgical procedure in a day surgery or inpatient setting; pain intensity had to be assessed 4–6 hours after initial administration using a validated pain measurement scale (ie, 5 point pain relief scale, 4 point …