Evid Based Nurs 8:52 doi:10.1136/ebn.8.2.52
  • Treatment

Review: no evidence exists that thrombolysis is better than heparin for reducing the risk of recurrent pulmonary embolism and death

 Q In patients with acute pulmonary embolism (PE), is initial thrombolysis more effective than heparin for reducing the risk of recurrent PE and death?


GraphicData sources:

Medline and EMBASE/Excerpta Medica (1980 to January 2003), Cochrane Library (Issue 1, 2003); and hand searches of reference lists of retrieved articles and abstracts of conference proceedings.

GraphicStudy selection and assessment:

published and unpublished randomised controlled trials (RCTs) with proper randomisation that compared thrombolysis with heparin for initial treatment of patients with objectively diagnosed symptomatic PE, and used objective methods to assess clinical outcomes. 2 independent reviewers assessed the methodological quality of individual trials based on allocation sequence and concealment, blinding, and follow up.


a composite of recurrent PE or death. Secondary …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article