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Evid Based Nurs 8:45 doi:10.1136/ebn.8.2.45
  • Treatment

Fluoxetine plus cognitive behavioural therapy was most effective for adolescents with major depressive disorder

Fluoxetine alone or fluoxetine plus cognitive behavioural therapy (CBT) v CBT alone or placebo for major depressive disorder in adolescents*

Outcome Event rates RRI (95% CI) NNH (CI)
*Abbreviations defined in glossary; RRI, NNH, and CI calculated using odds ratio in article.
Harm related adverse events 10% v 4.9% 107% (3 to 292) 19 (7 to 713)

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