Evid Based Nurs 8:44 doi:10.1136/ebn.8.2.44
  • Treatment

Short term coseasonal sublingual immunotherapy reduced the development of asthma in children with hay fever

 Q In children with allergic rhinoconjunctivitis (hay fever), does short term coseasonal sublingual immunotherapy reduce the development of asthma and seasonal hay fever symptoms?



randomised controlled trial.




blinded {patients, healthcare providers, and data collectors}*.

GraphicFollow up period:

3 years.


6 paediatric allergy centres in North Central Italy (Emilia, Tuscany, and Lazio).


113 children 4–16 years of age (mean age 8 y) with hay fever caused by grass pollen and clinical monosensitisation to grass pollen. Exclusion criteria: asthma, clinical sensitisation to other inhalant allergens, and previous immunotherapy for grass pollen allergy.


sublingual immunotherapy with an extract of mixed grass pollens given in a short term coseasonal protocol (4 mo each y …

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